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目的探讨清远市区和阳山县两地区儿童急性呼吸道感染呼吸道合胞病毒(RSV)和腺病毒(ADV)的临床特点。方法选择2012年8月至2014年4月期间,清远市人民医院和阳山县人民医院收治的儿童共450例,分别采用RT-PCR法检测呼吸道合胞病毒(RSV)和腺病毒(ADV)核酸,对比分析不同地区RSV和ADV的感染特点及在不同年龄段儿童、不同季节中的检出情况。结果清远市区和阳山县两地区RSV和ADV的感染均以清远市区的感染率为高。RSV在两地的男女发病率男性高于女性,而ADV在两地的男女发病率则几乎一致;RSV感染多发生于2~3岁的儿童中,阳性感染率为10.45%,多发生于冬季。ADV感染多发生于3~4岁的儿童中,阳性感染率为10.39%,多发生于冬季。结论清远市区和阳山县呼吸道合胞病毒和腺病毒的感染情况不同,但其感染均与儿童的性别、年龄以及季节等因素密切相关,可作为临床诊治和预防的基础依据。
Objective To investigate the clinical characteristics of respiratory syncytial virus (RSV) and adenovirus (AAV) in children with acute respiratory infections in both urban and Yangshan counties. Methods A total of 450 children admitted to Qingyuan People’s Hospital and Yangshan People’s Hospital from August 2012 to April 2014 were enrolled in this study. Respiratory syncytial virus (RSV) and adenovirus (ADV) were detected by RT-PCR. Nucleic acid, comparative analysis of different regions of RSV and ADV infection characteristics and in different age groups of children, detected in different seasons. Results The infection rates of RSV and ADV in Qingyuan urban area and Yangshan county were high in Qingyuan city. The prevalence of RSV in men and women in both regions was higher than that in women, while the prevalence of ADV in the two regions was almost the same. RSV infection occurred in children aged 2-3 years with a prevalence of 10.45%, most of which occurred in winter . ADV infection occurred in 3 to 4 years old children, the positive infection rate was 10.39%, occurred in winter. Conclusion The infection rates of respiratory syncytial virus and adenovirus are different in Qingyuan urban area and Yangshan county. However, the infection is closely related to the sex, age and season of children, which can be used as the basis of clinical diagnosis and prevention.