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脑灌注压(CPP)是决定脑血流量(CBF)的重要因素。因此,在对患病新生儿进行颅内压监护的同时应检测CPP。为此,作者观察了健康新生儿CPP的正常值,并对哭叫时CPP改变的意义进行了评价。受检者为36例出生5天内的健康新生儿,其中足月婴24例、早产婴12例。体重2.8±0.8kg.孕龄35±8周,测定时未给氧,血氧分析及酸硷平衡正常,呈安静或睡眠状态。用Ladd监护仪经前囟测定颅内压(ICP),多普勒新生儿血压计经上肢测定血压(BP).按CPP=BP(均值)—ICP|计算基础CPP。刺激足底哭叫时重复测定,再根据最高ICP和BP计算最低CPP值。本文结果显示(见附表),3组不同孕龄新生儿ICP均值相近,但是足月新生儿BP和CPP
Cerebral perfusion pressure (CPP) is an important factor in determining cerebral blood flow (CBF). Therefore, CPP should be tested in conjunction with intracranial pressure monitoring of the affected newborn. To do this, the authors looked at the normal values of CPP in healthy newborns and evaluated the significance of changes in CPP when crying. The subjects were 36 healthy newborns within 5 days of birth, of which 24 were full-term infants and 12 were premature infants. Weight 2.8 ± 0.8kg. Gestational age 35 ± 8 weeks, the test did not give oxygen, blood oxygen analysis and acid-base balance is normal, was quiet or asleep. Intracranial intracranial pressure (ICP) was measured using a Ladd monitor via the anterior fontanelle and blood pressure (BP) was measured from the upper extremity using a Doppler neonatal sphygmomanometer. CPP was calculated as CPP = BP (mean) -ICP |. Repeated determination of stimulation of plantar cries, and then calculate the lowest CPP value based on the highest ICP and BP. The results of this study (see attached table), three groups of newborns with different gestational age ICP mean similar, but full-term newborn BP and CPP