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目的:探讨超声脐动脉血流分析在肝内胆汁瘀积症孕妇中的临床价值。方法:1993年12月至1998年9月在本院住院分娩并接受超声脐动脉血流分析检查的ICP孕妇132例为ICP组和同期随机抽取正常孕妇60例为对照组,进行回顾性分析和总结,研究其济动脉血流收缩期末达率和舒张期末速率峰值的比值(S/D和博动指数(N)及与围产儿预后不良的关系。结果:ICP组的S/D和PI平均值均高于对照组(P<0.001);ICP组的S/D和PI结果异常的围产地预后不良发生率明显高于结果正常考(P<0.05和P<0.005)。结论:ICP孕妇的胎盘阻抗明显增高,其S/D和PI值明显高于正常妊娠孕妇,S/D和PI异常者其国产地预后不良发生率明显增高。因此,脐动脉血流分析是了解ICP孕妇胎盘功能,预测围产儿预后敏感而实用的监护手段。
Objective: To investigate the clinical value of umbilical artery blood flow analysis in pregnant women with intrahepatic cholestasis. Methods: Between December 1993 and September 1998, 132 pregnant women undergoing hospital delivery in our hospital and undergoing ultrasound umbilical artery blood flow analysis were included in the ICP group and 60 pregnant women randomly selected from the same period as the control group. The patients were retrospectively analyzed and compared To summarize the relationship between the ratio of peak end-systolic velocity and peak end-diastolic velocity (S / D and P index) and the poor prognosis of perinatal children in arteries.Results: The average S / D and PI in ICP group (P <0.001). The incidence of adverse outcomes of perinatal outcomes with abnormal S / D and PI findings in ICP group was significantly higher than those with normal results (P <0.05 and P <0.005). CONCLUSIONS: The placental impedance of pregnant women with ICP is significantly increased, and the S / D and PI values are significantly higher than those of normal pregnant women. The incidence of poor prognosis of ICP patients with abnormal S / D and PI is significantly increased. Therefore, umbilical artery blood flow analysis ICP placental function of pregnant women to predict the prognosis of perinatal sensitive and practical means of custody.