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以常染色体显性遗传方式的先天性Add- ison病至今尚未见国内、外文献报告。兹将我院所见的一个家系66人中的11例患者分析报告于后,并对其病因进行探讨。 研究对象,方法及结果 从我院内科内分泌病房住院患者——先证者郑某（例1）追索其四代家族共66人,其中10人已经死亡,11例为先天性Addison 病患者。对现存活的56人中的11例患者和31名健康人均作了较详细地临床调查。家族成员中无结核,肝炎及自身免疫疾病患者,有1例患枝气管哮喘。11例先天性Addison病患者为先证者,先证者的父亲,姑姑,妹妹1人,弟弟4人,儿子,姑表妹及侄儿,计男
To the autosomal dominant inheritance of Addison disease has not yet seen domestic and foreign literature. We will see a hospital in 66 cases of a family of 66 patients in the analysis report later, and its etiology to be explored. Subjects, Methods and Results From a patient with an endocrine ward in our hospital, Zheng Mou (Example 1) recalled 66 people from four generations of his family, of whom 10 had died and 11 had congenital Addison’s disease. 11 of the 56 active individuals and 31 healthy individuals were investigated in more detail. One of the family members had no TB, hepatitis and autoimmune disease and had bronchial asthma. Eleven patients with congenital Addison’s disease were probands. The proband’s father, aunt, and sister were 1, and their younger brother was 4, son, sister-in-law and nephew,