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近年来,国内外报导血清中甘油三酯(TG)升高与冠心病发病有关,特别与40-49岁男性患者的发病相关。这说明高甘油三酯血症可能是促成动脉粥样硬化发生的因素之一。血浆中TG的增高或降低与血浆中脂蛋白酯酶(LPL)的活性有一定的关系。这是因为LPL具有水解脂蛋白中TG为非酯化脂肪酸(NEFA)和甘油的作用。因此,LPL对血浆中TG说来是一个直接影响因素,也是研究高TG血症致动脉粥样硬化的一个重要环节。本文将LPL的特性、测定方法及其在
In recent years, reports of serum triglyceride (TG) increased at home and abroad and the incidence of coronary heart disease, especially with the incidence of male patients 40-49 years old. This shows that hypertriglyceridemia may contribute to the occurrence of atherosclerosis one of the factors. Plasma TG increased or decreased plasma lipoprotein lipase (LPL) activity has a certain relationship. This is because LPL has the effect of hydrolyzing TG to non-esterified fatty acids (NEFA) and glycerol in lipoproteins. Therefore, LPL is a direct factor in the plasma TG, and is also an important part of the study of atherosclerosis caused by hypertriglyceridemia. This article will LPL characteristics, determination methods and their