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目的观察经纤维支气管镜支气管肺泡灌洗对淹溺淡水污水后出现呼吸衰竭给予机械通气治疗的患者的疗效影响。方法35例淹溺污水后行机械通气治疗的患者,其中男性23例,女性12例;年龄18～67岁,平均年龄42.5岁。入院48 h内在机械通气状态下行经纤维支气管镜支气管肺泡灌洗治疗,比较入院时和入院48 h两组呼吸生理、呼吸力学及临床指标。结果抢救成功32例,死亡3例。与入院时相比,入院48 h氧合指数、呼吸频率、体温、吸气峰压等呼吸生理、呼吸力学及临床指标明显改善,比较上述两组指标,差异均有统计学意义(P<0.05),术中指脉氧监测无明显下降。结论经纤维支气管镜支气管肺泡灌洗在机械通气状态下治疗溺水所致呼吸衰竭的患者安全有效。
Objective To observe the curative effect of bronchial bronchoalveolar lavage (PBL) treated with mechanical ventilation on respiratory failure after flooding freshwater wastewater. Methods Totally 35 patients were treated with mechanical ventilation after inundation of waste water, including 23 males and 12 females, aged from 18 to 67 years with an average age of 42.5 years. Ventilation, bronchoscopy and bronchoalveolar lavage were performed under mechanical ventilation within 48 hours after admission. Respiratory physiology, respiration mechanics and clinical indexes were compared between the two groups during admission and 48 h after admission. Rescue success in 32 cases, 3 patients died. Compared with admission, the respiratory physiology, respiration mechanics and clinical indexes of oxygenation index, respiratory rate, body temperature and peak inspiratory pressure at 48 hours after admission were significantly improved. There were significant differences between the two groups (P0.05 ), Intraoperative finger pulse oxygen monitoring no significant decline. Conclusion Bronchoscopic bronchoalveolar lavage is safe and effective in the treatment of respiratory failure due to drowning in mechanical ventilation.