论文部分内容阅读
目的探讨消化道肿瘤死亡风险与饮用浅层地下水的关系。方法选择我国中部某河流域范围内4省中的10个县作为研究区域,调查其食管癌、胃癌、肠癌、肝癌4种消化道肿瘤2007—2013年死亡和2013年现患情况,应用Kaplan-Meier法比较4种消化道肿瘤不同研究指标生存率差异,应用Cox比例风险回归模型进行生存时间的环境影响因素分析。结果 4种消化道肿瘤生存率差异有统计学意义(P<0.05),与其他3种癌症相比,肝癌患者的生存率更低;不同年龄组间生存率差异有统计学意义(P<0.05);饮用浅井水胃癌患者死亡风险是不饮用浅井水胃癌患者的1.218倍。结论4种消化道肿瘤死亡风险随年龄增加而增大,饮用浅井水可能会增加胃癌患者死亡风险。
Objective To investigate the relationship between the risk of gastrointestinal cancer death and shallow groundwater drinking. Methods Ten counties in four provinces within a river basin in central China were selected as the study area to investigate the death and prevalence of four types of gastrointestinal cancer from 2007 to 2013 in esophageal cancer, gastric cancer, intestinal cancer and liver cancer. Kaplan -Meier method to compare the survival rate of four different types of gastrointestinal tumors survival index, the use of Cox proportional hazards regression model for the survival time of the environmental impact factors. Results The survival rates of four kinds of digestive tract tumors were significantly different (P <0.05). Compared with the other three kinds of cancer, the survival rates of patients with liver cancer were lower. The survival rates of different age groups were statistically significant (P <0.05 ). The risk of death from drinking well water gastric cancer was 1.218 times higher than that from drinking non-well water gastric cancer. Conclusion The risk of death from four kinds of gastrointestinal tumors increases with age. Drinking shallow water may increase the risk of death from gastric cancer patients.