论文部分内容阅读
目的:研究注射用头孢呋辛钠与注射用穿琥宁、葛根素注射液、氨甲苯酸注射液、酚磺乙胺注射液在0.9％氯化钠输液中配伍的稳定性。方法:采用紫外分光光度法考察各混合液室温条件下(15～25℃)配伍后0～6 h内含量的变化,同时观察pH值及外观的变化。结果:头孢呋辛钠与葛根素配伍后含量及外观稳定,但pH值有变化:与酚磺乙胺、穿琥宁、氨甲苯酸配伍后含量、外观、pH值均稳定。结论:头孢呋辛钠可与酚磺乙胺、穿琥宁、氨甲苯酸在0.9％氯化钠输液中配伍应用,但与葛根素配伍应用则不妥。
Objective: To study the stability of compatibility between cefuroxime sodium injection and chuanhuning injection, puerarin injection, trimethoprim injection and mesylate injection in 0.9% sodium chloride infusion. Methods: The content of the mixture in 0 ~ 6 h after mixing at room temperature (15 ~ 25 ℃) was investigated by UV spectrophotometry. The changes of pH value and appearance were also observed. Results: The content and appearance of cefuroxime sodium and puerarin were stable, but the pH value was changed. The content, appearance and pH value of cefuroxime sodium and p-toluic acid were stable after compatibility with psoriasisamide, chuanhuning and aminomethylbenzoate. Conclusion: Cefuroxime sodium can be used with phenylethylamine, chuanhuning and aminomethylbenzoic acid in 0.9% sodium chloride infusion, but the compatibility with puerarin is not suitable.