【摘 要】
：
目的 观察艾灸对哮喘发作期热哮证患者的临床疗效及肺功能、血清炎性因子的影响,为艾灸治热哮提供临床依据,并验证“热证可灸”的科学性.方法 选取2017年1月—2020年11月期间西安市第一医院老年呼吸科收治的支气管哮喘急性发作期热哮证患者130例,根据首次就诊顺序,随机分为治疗组和对照组,各65例.对照组采用布地奈德、硫酸沙丁胺醇雾化吸入治疗,治疗组在对照组基础上加用艾灸双侧肺俞穴.两组均持续治疗2周后,观察比较两组患者肺功能、血清炎性因子的变化.结果 治疗后治疗组总有效率92.3％(60/65),对照组总
【机 构】
：
西安市第一医院老年呼吸内科,陕西 西安710002;西安医学院第一附属医院呼吸与危重症医学科,陕西 西安710077;西安市第一医院中医科,陕西 西安710002
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目的 观察艾灸对哮喘发作期热哮证患者的临床疗效及肺功能、血清炎性因子的影响,为艾灸治热哮提供临床依据,并验证“热证可灸”的科学性.方法 选取2017年1月—2020年11月期间西安市第一医院老年呼吸科收治的支气管哮喘急性发作期热哮证患者130例,根据首次就诊顺序,随机分为治疗组和对照组,各65例.对照组采用布地奈德、硫酸沙丁胺醇雾化吸入治疗,治疗组在对照组基础上加用艾灸双侧肺俞穴.两组均持续治疗2周后,观察比较两组患者肺功能、血清炎性因子的变化.结果 治疗后治疗组总有效率92.3％(60/65),对照组总有效率80.0％(52/60),两组比较,差异有统计学意义(P<0.05).治疗后两组患者第1秒用力呼出量(Forced expiratory volume in one second,FEV1)、用力肺活量(Forced vital capacity,FVC)、呼气峰流速值(Peak expiratory flow,PEF)指标均较治疗前明显升高,差异有统计学意义(P<0.05);且治疗组治疗后FEV1、FVC、PEF指标均较对照组明显升高,差异有统计学意义(P<0.05).治疗后两组患者血清白细胞介素-8(Interleukin-8,IL-8)、降钙素原(Procalcitonin,PCT)水平较治疗前明显下降,血清白细胞介素-10(Interleukin-10,IL-10)水平均较治疗前明显升高,差异有统计学意义(P<0.05);且治疗组治疗后血清IL-8、PCT水平均较对照组明显下降,血清IL-10水平均较对照组明显升高,差异有统计学意义(P<0.05).结论 艾灸对支气管哮喘发作期热哮证患者确有疗效,不仅改善患者肺功能,且可抑制患者气道炎性反应.
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