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我们应用654-2配合激素治疗难治性肾小球肾炎8例,疗效满意,现报告如下。一、病例选择:本组8例均为用过激素和/或细胞毒药物治疗,但疗效不佳或无效而转本院的患者。其中慢性肾炎肾病型4例,紫癜性肾炎2例,狼疮性肾炎2例。二、治疗方法:654-2剂量从每次30mg,1日3次,逐日增加直至每次100mg,1日3次,以病人耐受为度,到出现明显阿托品化为止,继续服用一个月。有效后逐渐撤减激素和654-2的用量。
We use 654-2 with hormone treatment of refractory glomerulonephritis in 8 cases, the effect is satisfactory, are as follows. First, the case selection: The group of 8 patients were treated with hormones and / or cytotoxic drugs, but ineffective or ineffective and transferred to the hospital patients. Including chronic nephritis kidney disease in 4 cases, 2 cases of purpura nephritis, lupus nephritis in 2 cases. Second, the treatment: 654-2 dose from each 30mg, 1 day 3 times, increasing daily until each 100mg, 1 3 times, the patient’s tolerance for the degree until obvious atropine up, continue to take a month. Effective withdrawal after gradual withdrawal of hormones and the amount of 654-2.