论文部分内容阅读
A green and efficient synthesis of 3-pyrazolyl indoles was developed by the cyclocondensation reaction of β-ethylthio-β-indolyl-a,β-unsaturated ketones with semicarbazide hydrochloride as hydrazine equivalent in the presence of 3 equiv.of PEG-400(1a/PEG mole ratio of 1:3) in reflux water.This procedure did not require toxic hydrazine and product purification,eliminating the use of toxic liquid chemicals.