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二尖瓣脱垂(MVP)系常见病,其发病率为5%~10%.最初认为本病是一种良性综合征,后来人们发现它有严重并发症,如二尖瓣关闭不全,感染性心内膜炎、心律失常、卒中或短暂性脑缺血发作(TIA)等,脑血管并发症则因心源性栓子所致,血小板活性对血栓形成起重要作用.血小板活性可由血浆中血小板因子4(PF_4)含量测定来衡量,这种因子系血小板聚集的标记蛋白.故本文作者用MVP患者的血浆PF_4的含量测定来推测血小板活性程度.作者对55例正常人(男29、女26,平均年龄38
Mitral valve prolapse (MVP) is a common disease, the incidence rate of 5% to 10% .First thought this disease is a benign syndrome, later people found it has serious complications, such as mitral regurgitation, infection Endocarditis, arrhythmia, stroke or transient ischemic attack (TIA), cerebrovascular complications due to cardiogenic emboli caused by platelet activity plays an important role in thrombosis.Platelet activity by the plasma The platelet factor 4 (PF_4) assay was used to measure the level of platelet aggregation marker protein.Therefore, the authors use the plasma PF_4 content of MVP patients to estimate the degree of platelet activity.According to 55 normal subjects (male 29, female 26, the average age of 38