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目的探讨全麻复合硬膜外麻醉对胃癌根治术患者应激及炎性反应的影响。方法选取我院收治的50例行胃癌根治术的患者,随机平均分成观察组和对照组,对照组实施全身麻醉,观察组实施全麻复合硬膜外麻醉,观察两组患者的应激反应以及炎性反应。结果观察组患者在麻醉后30min和术后2h血浆当中的血糖、皮质醇、TNF-α、IL-6的水平都明显低于对照组患者,P<0.05。结论对于行根治术的胃癌患者,行全身麻醉联合硬膜外麻醉可以取得更好的麻醉效果,值得在临床上推广和应用。
Objective To investigate the effects of general anesthesia combined with epidural anesthesia on stress and inflammatory response in patients with gastric cancer undergoing radical operation. Methods Fifty patients undergoing radical gastrectomy in our hospital were randomly divided into observation group and control group. The control group was given general anesthesia. The observation group was given general anesthesia combined with epidural anesthesia. The stress response of the two groups was observed. Inflammatory reaction. Results The levels of blood glucose, cortisol, TNF-α and IL-6 in the observation group were significantly lower than those in the control group at 30 min and 2 h after anesthesia (P <0.05). Conclusion For radical gastrectomy patients with gastric cancer, general anesthesia combined with epidural anesthesia can achieve better anesthetic effect, it is worth in the clinical promotion and application.