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Laser refractive surgery is one of the most performed surgical procedures in the world. Although regard-ed safe and efficient, it has side effects. All of the laser based refractive surgical procedures invoke ceal nerve injury to some degree. The impact of this denervation can range from mild discomfort to neuro-trophic ceas. Currently, three techniques are widely used for laser vision correction: small incision lenticule extraction, laser-assisted keratomileusis in situ and photorefractive keratotomy. Each of these techniques affects ceal innervation differently and has a different patt of nerve regeneration. The purpose of this review is to summarize the different underlying mechanisms for ceal nerve injury and compare the different patts of ceal reinnervation.