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目的：比较胃癌高发区（淮安市）和低发区（邳州市）自然人群在生活方式和疾病史方面的异同，寻求胃癌高发流行的可能原因。方法：用整群抽样的方法在两地选取5年及5年以上的常住居民作为调查对象，在一定的时间内用统一的调查表对所有的对象进行调查。各调查指标用X2检验进行统计分析。结果：本次研究中获得523个有效作本（淮安270个，邳州253个）。X2检验结果表明淮安市居民吃肉食的频率、慢性胃炎史、消化性溃疡史、家族胃癌史、自觉消化系统症状及饮茶率均高于邳州市居民，而邳州市居民食葱蒜频率和男性吸烟率明显高于淮安市居民。结论：胃癌高低发区居民在生活方式和疾病史等方面存在较大的差异。
OBJECTIVE: To compare the differences in lifestyle and disease history among natural populations from high prevalence areas (Huai’an City) and low incidence areas (Zhangzhou City), and to look for possible causes of high prevalence of gastric cancer. Methods: Using the method of cluster sampling to select five-year and five-year permanent residents as the survey objects in the two places, a unified questionnaire was used to investigate all subjects in a certain period of time. The survey indicators were statistically analyzed using the X2 test. Results: 523 valid samples were obtained in this study (270 in Huai’an and 253 in Chenzhou). The results of X2 test showed that the frequency of eating meat, chronic gastritis, peptic ulcer, family cancer, conscious digestive system symptoms, and tea drinking rate were all higher among the residents of Huai’an City than those of the residents of Luzhou City. The smoking rate of males was significantly higher than that of Huai’an residents. Conclusion: The residents of high and low incidence areas of gastric cancer have great differences in lifestyle and disease history.