16例遗传性小脑型共济失调的临床分析

• 作 者: 蒋布军
• 机 构: 湖北医学院附二医院分院,
• 出 处: 湖北医学院学报
• 发表日期: 1992年04期
• 关键词: 小脑型共济失调 小脑共济失调 发病年龄 遗传 促发因素 临床分析 断层摄影术 细菌感染 散发病例 遗传性共济失调

作者报导小脑型共济失调16例,对其发病因素进行临床分析。遗传组和散发组各占50%,前者平均发病年龄29.5岁,后者平均年龄34.5岁。有遗传史者,其下一代发病年龄有提前趋势。女性激素的急剧变化可能为疾病的重要促发因素之一。散发病例中病毒或细菌感染在疾病的发生和发展中可能为诱因之一。

The authors report 16 cases of cerebellar ataxia, the clinical analysis of the incidence of factors. Genetic groups and sporadic groups each accounted for 50%, the former average age of onset of 29.5 years, the latter average age of 34.5 years. A genetic history, the age of onset of their next generation have an earlier trend. The dramatic change in female hormones may be one of the major contributors to the disease. Sporadic cases of virus or bacterial infection in the pathogenesis and development may be one of the incentives.