论文部分内容阅读
[目的]按照WHO批准的诊断标准,以骨矿含量(BMC)为诊断指标,建立四川省50岁及以上妇女骨质疏松的筛检工具,为骨质疏松筛检和诊断的进一步发展提供依据和方法学参考。[方法]利用四川省50岁及以上妇女的年龄、身高、体重、绝经年龄,基于双能X线骨密度仪的腰椎(L2-4)BMC等数据,采用Fisher判别分析建立四川省妇女骨质疏松的筛检工具,并利用ROC曲线评价筛检效果。[结果]提出了四川省妇女骨质疏松(OP)的筛检工具,即Q=0.8体重-0.7年龄,ROC曲线下面积为0.828(P﹤0.05)。判定准则即为:Q≥9,判为无OP危险性;Q﹤9,判为有OP危险性。此时的灵敏度为91.7%,特异度为48.5%。[结论]新筛检工具筛检准确性较高,具有筛检价值,建议使用此筛检工具对四川省妇女进行骨质疏松的筛检。
[Objective] To establish a screening tool for osteoporosis in women aged 50 years and above in Sichuan Province based on the diagnostic criteria approved by the WHO and the bone mineral content (BMC) as the diagnostic index to provide the basis for the further development of osteoporosis screening and diagnosis And methodological reference. [Methods] Based on the data of age, height, weight, age at menopause, and lumbar spine (L2-4) BMC in 50 years old and above women in Sichuan Province, Fisher discriminant analysis was used to establish the bone mass of women in Sichuan province Loose screening tools, and the use of ROC curve evaluation of screening results. [Results] The screening tool for osteoporosis (OP) in women in Sichuan Province was proposed, that is, Q = 0.8 body weight - 0.7 years of age. The area under the ROC curve was 0.828 (P <0.05). Decision criteria that is: Q ≥ 9, adjudged no risk of OP; Q <9, adjudged to have the risk of OP. At this time, the sensitivity was 91.7% and the specificity was 48.5%. [Conclusion] The new screening tool has high screening accuracy and screening value. We recommend using this screening tool to screen the women with osteoporosis in Sichuan Province.