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目的 探讨基于CT三维重建图像分割技术运用数字化技术测量腔性骨肿瘤体积.方法 2010年1月至8月,收集20例腔性骨肿瘤患者的多层螺旋CT扫描的薄层原始数据(DICOM格式),男11例,女9例.术前将原始数据导入数字化骨科临床研究平台系统(SuperImage orthopedics edition 1.1,Cybermed Ltd),通过该系统的三维图像分割技术、自由剖面选择技术、区域充填及三维组合式测量技术计算腔性骨肿瘤体积及骨肿瘤最大径;术中通过水溶剂法或骨水泥法实测骨肿瘤体积;术后再通过公式法计算骨肿瘤体积.数字化技术测量方法由天津医院、同济医院各自完成,并取均值.结果 应用数字化测量法、实体肿瘤测量法、公式计算法测量出的腔性骨肿瘤体积值平均为(14.92±7.34)mm3、(16.65±6.95)mm3、(34.29±15.70)mm3;其中数字化测量法与实体肿瘤测量法所测得体积数据差异无统计学意义,而实体肿瘤测量与公式计算法所测体积数据差异有统计学意义.实体肿瘤体积值与肿瘤最大径值之间的相关系数r=0.325(P=0.162),肿瘤体积与肿瘤直径之间的线性相关性不明显.结论 应用数字化体积测量技术可较为精准、高效、可重复性地测量腔性骨肿瘤的体积.“,”Objective To discuss the measurement of bone tumor volume on the basis of three dimensional images segmentation technology. Methods Twenty patients with lacunar bone tumor from Tianjin hospital and Tongji hospital were included in the study from January 2010 to August 2010. There were 11 males and 9 females. Each patient was exposed to spiral CT preoperatively. Then these primitive CT dates were imported into digital orthopedics clinical research platform (SuperImage orthopedics edition 1.1, Cybermed Ltd). The volume and maximum diameter of bone tumor were measured before operation by three-dimensional reconstruction technology. The actual tumor volume was measured during the operation. The tumor volume was also calculated from plain X-rays and CT scans as ellipsoidal or cylindrical depending on the tumor configuration and presence or absence of a soft tissue component. Results The tumor volume was measured to be (14.92±7.34) mm3, (16.65±6.95) mm3 and (34.29±15.70) mm3 using three-dimensional reconstruction technology, intraoperative elevation, and traditional radiograph measurement separately. It was found that there was no difference regarding the outcomes of measurement between three-dimensional reconstruction technology and gross intraoperative measurement. But obvious difference was detected between gross intraoperative measurement and traditional radiograph measurement. Coefficient of correlation between diameter and volume of bone tumor was 0.325 (P=0.162). Conclusion Digital measurement is a precise, efficient,convenient and repeatable method for bone tumor measurement.