论文部分内容阅读
虽然对卵巢粒层细胞瘤granulosa cell tumor (GCT)进行广泛研究,但其行为仍未能预测,尤其对早期病变缺乏预后性因素,故复发率为9％～38％,而临床晚期和复发是预后不良的指标。回顾性分析40例GCT的临床及病理资料,包括结局及瘤细胞有丝分裂计数、核异型的检测,其中32例进行了石蜡包埋存档的瘤组织块中Ki-67、c-myc、p21-ras、c-erbB_2、p53免疫组化检测,以期发现GCT患者的预后与上述指标间的关系。 40例中ⅠA期20例,ⅠC期11例,ⅡC或ⅢC期9例。复发者中ⅠA期6例(30％),ⅠC期4例(36％),
Although widely studied on granulosa cell tumor (GCT) in ovarian cell carcinoma, its behavior is still unpredictable, especially in the absence of prognostic factors for early lesions, so the recurrence rate is 9% ~ 38%, while the late clinical and recurrence is Prognosis of poor prognosis. The clinical and pathological data of 40 cases of GCT were retrospectively analyzed, including the outcome and detection of mitotic count and nuclear atypia in 32 cases of tumor tissues, including Ki-67, c-myc and p21-ras , C-erbB_2, p53 immunohistochemistry in order to find the prognosis of GCT patients with the above indicators. 40 cases of Ⅰ A in 20 cases, Ⅰ C in 11 cases, Ⅱ C or Ⅲ C in 9 cases. Among the relapsers, 6 cases (30%) were in stage IA, 4 cases (36%) in stage IC,