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目的:探讨急性脑血栓的动脉插管溶栓治疗的疗效及评价。材料与方法:经临床和 CT 确诊为脑血栓15例中,男9例,女6例,年龄46～69岁,平均55.8岁。发病至溶栓术时间以24小时之内者为多,11例,采用 Seldinger 技术,导管置血管闭塞部位或近闭塞部位灌注纤溶剂。用尿激酶(UK)10例,16～125万单位;蝮蛇抗栓酶(Svate-3)5例,2.5～7.5单位。结果:15例中2例即刻基本治愈,5例显著好转,7例好转;血管再通率80%(12/15),即刻有效率93.3%(14/15);出院时基本治愈8例,显著好转4例,好转2例,总有效率93.3%。结论:动脉内溶栓针对性强,疗效迅速、显著,是一种有价值的治疗手段;溶栓愈早愈好,用药剂量以不出现副作用给最大量,溶栓术后继续抗栓抗凝可增加疗效,故易普及推广。
Objective: To investigate the efficacy and evaluation of arterial intubation thrombolysis in patients with acute cerebral thrombosis. MATERIALS AND METHODS: Fifteen cases of cerebral thrombosis were diagnosed clinically and CT. There were 9 males and 6 females, aged 46-69 years, with an average age of 55.8 years. Incidence to thrombolytic time within 24 hours were more, 11 cases, the use of Seldinger technology, catheter occlusion of blood vessels near the site of occlusion or fibrinolysis. 10 cases of urokinase (UK), 16 to 1.25 million units; viper antithrombin enzyme (Svate-3) in 5 cases, 2.5 to 7.5 units. Results: Two of 15 cases were cured immediately, 5 cases improved significantly and 7 cases improved. The recanalization rate was 80% (12/15), immediate efficiency was 93.3% (14/15) Significant improvement in 4 cases, improved in 2 cases, the total efficiency of 93.3%. Conclusion: Intra-arterial thrombolysis is highly targeted and has rapid and significant curative effect. It is a valuable therapeutic method. The earlier the thrombolytic therapy is, the more dosage is needed to avoid the side effects to the maximum amount. Thrombolytic anticoagulation continues after thrombolysis Can increase the efficacy, it is easy to popularize.