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C反应蛋白是在患某些疾病时出现于血清中的一种特殊蛋白质,因其能沉淀肺炎球菌菌体的C多糖而得名,是一种传统的炎症标志物。动脉粥样硬化是一种慢性炎症性疾病,炎症从动脉粥样硬化斑块的形成、生长到破裂,构成了其全部病程的基础。随着研究的深入,发现C反应蛋白与动脉粥样硬化的关系密切,并可能具有重要应用价值。本文综述了C反应蛋白与动脉粥样硬化研究的最新进展,并对未来研究方向进行了展望。
C-reactive protein is a special protein found in serum when suffering from certain diseases. It is a traditional inflammatory marker because of its ability to precipitate the C polysaccharide of pneumococcal bacteria. Atherosclerosis is a chronic inflammatory disease that develops from atherosclerotic plaque into rupture and forms the basis of its full course. With further research, we found that C-reactive protein and atherosclerosis are closely related, and may have important application value. This review summarizes recent advances in the research of C-reactive protein and atherosclerosis, and looks forward to future research directions.