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目的：观察ＲＰＤｓ患者唾液流量、酸碱平衡及唾液中变形链球菌数量，以深入探讨ＲＰＤｓ对口腔微生态环境的影响机制及特点。方法：收集患者５分钟非刺激性全唾液于干燥清洁瓶内，计算单位时间内唾液分泌总量（流率ｍＬ／ｍｉｎ），并用精密ｐＨ试纸测定唾液ｐＨ值；根据文献采用塑料条法测定唾液中变链菌数。结果：①患者戴用ＲＰＤｓ后，唾液流率有所减低，唾液ｐＨ值有所升高，但随着戴用时间延长，它们又逐渐恢复正常；②患者戴用ＲＰＤｓ后唾液中变形链球菌数量增加。结论：戴用ＲＰＤｓ可导致患者唾液分泌减少，酸碱平衡破坏及致龋微生物变形链球菌数量增加。这对深入认识ＲＰＤｓ对口腔微生态影响的机理及临床防治ＲＰＤｓ对口腔健康的破坏具有一定的实践意义。
OBJECTIVE: To observe salivary flow, acid-base balance and the amount of Streptococcus mutans in saliva of patients with RPDs to explore the mechanism and characteristics of RPDs on oral micro-ecological environment. Methods: The patients were collected for 5 minutes in non-irritating whole saliva in a dry clean bottle, the total amount of saliva secretion per unit time (flow rate mL / min) was calculated, and the saliva pH value was measured with a precision pH test paper. According to the literature, saliva Streptococcus mutans. Results: ①The salivary flow rate decreased and the salivary pH increased after wearing RPDs, but they returned to normal with the prolongation of wearing time. ② The amount of S. mutans in saliva after wearing RPDs increase. Conclusion: Wearing RPDs can lead to decreased salivary secretion, acid-base balance, and the increase of cariogenic streptococcus mutans. It is of practical significance to understand the mechanism of RPDs on oral microecology and to prevent and cure RPDs on oral health.