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1 临床资料 患者女性,28岁。患者因手及足癣自1992年1月6日起服用酮康唑0.2/d,25 d后出现两颞侧头痛,巩膜、皮肤黄染,尿色加深至本院就诊。肝功能:ALT 591 U,HBsAg、HBsAb等乙肝免疫检测均阴性。即停用酮康唑,予以肝泰乐、维生素C、熊去氧胆酸等保肝、利胆治疗,头痛有所缓解,但巩膜、皮肤黄染无明显减轻,于2月21日入院进一步诊治。发现黄疸后无发热、乏力和肝区疼痛,食欲如常,无恶心、呕吐,无皮肤搔痒。既往无病毒性肝炎密切接触史、药物过敏和输血史。入院
1 clinical data patients female, 28 years old. Patients with hand and foot ringworm since January 6, 1992 from taking ketoconazole 0.2 / d, 25 days after the emergence of two temporal headache, sclera, skin yellow dye, dark urine to deepen our hospital. Liver function: ALT 591 U, HBsAg, HBsAb and other hepatitis B immune tests were negative. That is, the withdrawal of ketoconazole, to liver Tailor, vitamin C, ursodeoxycholic acid and other liver, gallbladder treatment, headache eased, but the sclera, skin yellow dye no significant reduction in admission on February 21 further Diagnosis and treatment. Found jaundice after no fever, fatigue and liver pain, normal appetite, no nausea, vomiting, no skin itching. Past history of close contact with viral hepatitis, drug allergy and transfusion history. Admission