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为进一步研究幽门螺杆菌 (Helicobacterpylori,H.pylori)感染与儿童胃炎的关系 ,对我科1998年至2000年间500例3岁～15岁儿童胃镜活检组织进行组织学和H.pylori观察 ,按Sydney胃炎标准对病变分级 ,分析和探讨H.pylori感染与儿童胃炎发展变化的关系。结果表明 :40.4 %的儿童胃炎与H.pylori感染有关 ;而且炎症的程度、淋巴滤泡的形成、嗜酸细胞增多及幽门腺萎缩明显高于无H.pylori感染的儿童胃炎。提示上海地区儿童胃炎有很高的H.pylori感染率 ,H.pylori感染与儿童胃炎关系密切 ,儿童H.pylori胃炎的胃粘膜病理变化比非H.pylori感染者严重。
To further study the relationship between Helicobacter pylori (H.pylori) infection and gastritis in children, we retrospectively analyzed the histological and H.pylori biopsies of 500 children aged 3-15 years from 1998 to 2000. According to the results of Sydney Gastritis criteria for the classification of lesions, analysis and discussion of H.pylori infection and the development of children with gastritis. The results showed that gastritis was associated with H.pylori infection in 40.4% of children, and the degree of inflammation, lymphoid follicle formation, eosinophilia and pyloric atrophy were significantly higher than those in children without H.pylori infection. It is suggested that there is a high H.pylori infection rate in children with gastritis in Shanghai. H.pylori infection is closely related to gastritis in children. The gastric mucosal pathological changes of children with H.pylori gastritis are more serious than those without H.pylori infection.