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目的观察米力农联合正压机械通气治疗急性心肌梗死并发急性左心衰竭的疗效。方法 90例急性心肌梗死并发急性左心衰竭患者,随机分为对照组与实验组,各45例。对照组采用常规治疗,实验组在对照组基础上加用米力农联合正压机械通气进行治疗,连续治疗5 d。观察两组患者心功能改善情况及出现的不良反应。结果治疗后,对照组患者心功能改善总有效率为55.56%,实验组患者心功能改善总有效率为80.00%,实验组患者心功能改善的总有效率明显高于对照组,差异具有统计学意义(P<0.05);对照组患者死亡率为20.00%,实验组患者死亡率为8.89%,对照组患者死亡率明显高于实验组,差异具有统计学意义(P<0.05)。两组患者均无明显不良反应出现。结论米力农联合正压机械通气治疗急性心肌梗死并发急性左心衰竭疗效显著,值得在临床中推广使用。
Objective To observe the effect of milrinone combined with positive pressure mechanical ventilation in patients with acute myocardial infarction complicated by acute left heart failure. Methods Ninety patients with acute myocardial infarction complicated by acute left heart failure were randomly divided into control group and experimental group, with 45 cases in each group. The control group was treated with conventional therapy. The experimental group was treated with Milrinone plus positive pressure mechanical ventilation on the basis of the control group, and the treatment was continued for 5 days. Two groups of patients to observe the improvement of cardiac function and adverse reactions. Results After treatment, the total effective rate of heart function improvement was 55.56% in control group and 80.00% in experimental group. The total effective rate of cardiac function improvement in experimental group was significantly higher than that in control group, the difference was statistically significant (P <0.05). The mortality rate in the control group was 20.00%, the mortality rate in the experimental group was 8.89%, and the mortality rate in the control group was significantly higher than that in the experimental group (P <0.05). No adverse reactions occurred in both groups. Conclusion Milrinone combined with positive pressure mechanical ventilation in the treatment of acute myocardial infarction complicated by acute left heart failure has significant curative effect and is worth popularizing in clinic.