【摘 要】
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Spinal cord injury(SCI)is a severe condition characterized by neurological dysfunction,dependence,respiratory fail-ure,psychological morbidities,and an increase
【机 构】
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Laboratory of Aging and Cancer Biology of Zhejiang Province,School of Medicine,Hangzhou Normal Unive
论文部分内容阅读
Spinal cord injury(SCI)is a severe condition characterized by neurological dysfunction,dependence,respiratory fail-ure,psychological morbidities,and an increased mortality rate[1].Globally,its incidence ranges from 250,000 to 500,000 annually,resulting in tremendous psychological and financial burdens[1].Because of limited axonal regrowth and glial scar formation in wound healing after SCI in humans,the adult central nervous system(CNS)has very low regenerative ability,leading to permanent neu-rological impairment[2].SCI has devastating outcomes,including a high prevalence of chronic pain[3]and altered sensory function,and effective treatment is still lacking[4].
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