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回顾分析了位于喉前庭部位均属于Ⅲ期的喉鳞癌患者185例。初诊时均无区域性或远隔部位转移。应用综合治疗者153例,放射治疗32例。按照Yacobsson标准对肿瘤细胞形态学进行了分析,结果属于Ⅰ级恶性程度者45例,Ⅱ级105例,Ⅲ级35例。结果45例属于Ⅰ级的患者全部生存3至10年无肿瘤复发和转移。Ⅱ级者中有63例得到相同结果,其余42例在治疗结束后不同时期死于肿瘤。35例Ⅲ级者均在治疗结束后1年之内死于肿瘤扩展。由此可见喉癌患者的预后不仅取决于肿瘤扩展的范围,也取决于肿瘤细胞的形态学分化程
We retrospectively analyzed 185 cases of laryngeal squamous cell carcinoma belonging to stage Ⅲ in the laryngeal vestibule. No regional or distant parts of the first visit when the transfer. The application of comprehensive treatment in 153 cases, 32 cases of radiation therapy. Tumor cell morphology was analyzed according to the Yacobsson standard. As a result, there were 45 patients with grade Ⅰ malignancy, 105 patients with grade Ⅱ and 35 patients with grade Ⅲ. Results 45 patients with grade Ⅰ all survived 3 to 10 years without tumor recurrence and metastasis. Sixty-three of the grade II patients achieved the same result, and the remaining 42 patients died of tumors at different stages after treatment. 35 patients with grade Ⅲ died of tumor expansion within 1 year after the end of treatment. Thus, the prognosis of patients with laryngeal cancer depends not only on the extent of tumor expansion, but also on the morphological differentiation of tumor cells