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目的比较急性前壁心肌梗死(AMI)发病6h内溶栓与急诊介入治疗的临床效果。方法选取2010年6月-2013年3月收治的AMI患者90例,随机分为研究组与对照组各45例,对照组予以溶栓治疗,研究组则予以介入治疗,分析比较2组临床治疗疗效。结果研究组再灌注成功率明显高于对照组,6h肌钙蛋白(c Tn T)水平和肌酸激酶同工酶(CK-MB)峰值均明显高于对照组,住院时间短于对照组,心功能LVEF明显高于对照组,ST回落时间短于对照组,差异均有统计学意义(P<0.05)。结论 AMI患者于6h内应用介入治疗可提高再灌注率、降低病死率,改善预后质量,效果更为显著,临床应用价值高。
Objective To compare the clinical efficacy of thrombolysis and emergency intervention within 6 hours after acute anterior myocardial infarction (AMI). Methods Ninety patients with AMI admitted from June 2010 to March 2013 were randomly divided into study group and control group with 45 cases in each group. The control group received thrombolytic therapy while the study group was treated with interventional therapy. Two groups of clinical treatment were compared Efficacy. Results The success rate of reperfusion in the study group was significantly higher than that in the control group. The levels of cTn T and creatine kinase K (CK-MB) at 6h were significantly higher than those of the control group, Heart function LVEF was significantly higher than the control group, ST drop time was shorter than the control group, the difference was statistically significant (P <0.05). Conclusions Interventional therapy in AMI patients can improve the reperfusion rate, reduce the mortality and improve the prognosis quality within 6 hours. The effect is more significant and the clinical value is high.