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目的：了解口含干扰素片治疗儿童反复呼吸道感染（ＲＲＩ）的效果。方法：检测了口含干扰素和常规治疗组ＲＲＩ患儿在治疗前后Ｔ淋巴细胞亚群和血清ｓＩＬ２Ｒ水平，并与正常健康儿童对照。结果：口含干扰素片治疗后患儿ＣＤ３、ＣＤ４、ＣＤ４／ＣＤ８均显著升高，ＣＤ８水平和血清ｓＩＬ２Ｒ水平显著降低，ＣＤ４、ＣＤ８、ｓＩＬ２Ｒ水平与正常对照组相比均无明显差异，经常规治疗的患儿仅ＣＤ４、ＣＤ４／ＣＤ８显著升高，ＣＤ３、ＣＤ８水平和血清ｓＩＬ２Ｒ水平在治疗前后均无显著差异，与正常对照组相比，除ＣＤ４外其余各项指标均差异显著，且口含干扰素片治疗后患儿ＣＤ３、ＣＤ４／ＣＤ８显著高于常规治疗的患儿（Ｐ＜０．００１），而ＣＤ８、ｓＩＬ２Ｒ水平则显著低于常规治疗组（Ｐ＜０．００１）。结论：口含干扰素片治疗后患儿的细胞免疫状态优于常规治疗的患儿。
Objective: To understand the effect of oral interferon tablets in the treatment of children with recurrent respiratory tract infections (RRI). Methods: T lymphocyte subsets and serum sIL2R levels in RRI children with oral interferon and routine therapy were detected before and after treatment, and compared with normal healthy children. Results: The levels of CD3, CD4 and CD4 / CD8 in children with oral interferon tablets after treatment were significantly increased, CD8 levels and serum sIL 2R levels were significantly decreased, CD4, CD8, sIL 2R levels compared with the normal control group Significant differences in the treatment of children with only CD4, CD4 / CD8 significantly increased, CD3, CD8 levels and serum sIL 2R levels before and after treatment were no significant difference compared with the normal control group, in addition to the rest of the CD4 The indexes of CD3 and CD4 / CD8 in children with oral interferon tablets were significantly higher than those in routine treatment (P <0.001), while the levels of CD8 and sIL2R were significantly lower than those in the conventional treatment group (P <0.001). Conclusion: The cellular immune status of children with oral interferon tablets is better than that of routine treatment.