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目的了解非辩证的应用具有活血化瘀作用的中药注射剂对患者血液流变学指标的影响。方法随机选择40例住院治疗的具有心脑血管系统疾病的患者,将其随机分成3组,在西医常规用药治疗的基础上根据医生的习惯未经中医辨证的分别加用具有活血化瘀作用的中药注射剂丹参(主要成分为丹参多酚酸盐)、血栓通(主要成分为三七总皂苷)、瓜蒌皮(主要成分瓜蒌皮提取液),静脉滴注1个疗程14 d,分别于用药前及用药1个疗程后抽血测定患者的血液流变学指标。结果①在治疗前后40例患者的血液流变学指标无明显改变;②在亚组分析中,三种药物在治疗前后血液流变学指标也均无明显改变。结论非辩证的应用具有活血化瘀作用的中药注射剂对血液流变学指标无明显影响,不能降低血液黏度。
Objective To understand the effect of non-dialectical application of traditional Chinese medicine injection on blood rheology in patients with blood-activating and blood-stasis effect. Methods Forty patients with cardiovascular and cerebrovascular diseases who were hospitalized were randomly selected and divided into three groups randomly. On the basis of the conventional treatment of Western medicine, according to the physician’s habits, they were treated with the methods of promoting blood circulation and removing blood stasis Radix Salviae Miltiorrhizae (the main component is Radix Salviae Miltiorrhizae), Xueshuantong (the main component is Panax notoginseng saponin), the melon skin (the main component Melon extract), one course of intravenous drip for 14 days, Before treatment and medication after a course of treatment of patients with blood rheology indicators. Results ① Before and after treatment, there were no significant changes in the hemorrheological parameters in 40 patients. ② In the subgroup analysis, there was no significant change in the hemorrheological indexes of the three drugs before and after treatment. Conclusion Non-dialectical application of Chinese medicine injection with the function of promoting blood circulation and removing blood stasis has no obvious effect on hemorheology indexes, and can not reduce blood viscosity.