Aspirin suppresses growth of human gastric carcinoma cell by inhibiting survivin expression

• 作 者: Li Yang Huaijun Zhu Dongxiao L
• 机 构: DepartmentofGeneralSurgery,DivisionofClinicalPharmacy,DepartmentofPharmacology
• 出 处: 生物医学研究杂志：英文版
• 发表日期: 2011年4期
• 关键词: SURVIVIN 胃癌细胞 阿司匹林 生长 SURVIVIN 时间依赖性 细胞凋亡 蛋白水平 aspirin survivin gastric cancer
• 基金项目: This study was supported by the Science Foundation of Jiangsu Province for Institutions of Higher Learning （No. 08kjb320004）.

Regular use of aspirin (ASA) could reduce the risk of gastric cancer although the precise mechanism remains unclear.Down-regulation of survivin may be one of the cyclooxygenase-independent mechanisms whereby ASA induces apoptosis of gastric cancer cell.In