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最近发现的内皮素是一种含有21个氨基酸的血管活性肽,可能是迄今所认识的最强力的血管收缩因子,参与了脑血管痉挛的病理。本文将内皮素的基础研究及其临床意义加以综述。
The recently discovered endothelin is a 21 amino acid vasoactive peptide that may be the most potent vasoconstrictor known to date and is involved in the pathogenesis of cerebral vasospasm. This article summarizes the basic research of endothelin and its clinical significance.