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目前,随着中西医结合事业的兴起,中西药物联合并用的机率越来越高。中西药物联合组方的制剂不断问世,剂型日益增多,因此,探讨中西药物联用而产生的不良反应具有一定的现实意义。 1 在药代动力学方面,中西药合用,可影响某些药物在体内的吸收、分布、代谢、排泄。 1.1 影响药物的吸收,如含颠茄类生物碱的中药与洋地黄类强心甙合用,因前者可减慢胃排空和胃肠蠕动,
At present, with the rise of the integrated traditional Chinese and western medicine, Chinese and western medicine are more and more likely to be used jointly. The preparation of Chinese and Western medicine combined with the group of prescription continue to come out, dosage forms are increasing, therefore, to explore the adverse reactions of Chinese and Western medicine combined has some practical significance. In pharmacokinetics, the combination of Chinese and Western medicine can affect the absorption, distribution, metabolism and excretion of certain drugs in the body. 1.1 affect the absorption of drugs, such as belladonna alkaloids containing traditional Chinese medicine and digitalis glycosides combined, because the former can slow down gastric emptying and gastrointestinal motility,