老年人脑皮质下斑点状病灶的MRI病理基础研究

• 作 者: 徐跃成 陈星荣 沈天真 方军 叶诸榕
• 机 构: 上海医科大学附属华山医院放射科,上海医科大学附属华山医院放射科,上海医科大学附属华山医院放射科,上海医科大学附属华山医院病理科,上海医科大学病理解剖教研室 (200040),(200040),(200
• 出 处: 临床神经科学
• 发表日期: 1993年01期
• 关键词: MRI 脑皮质 斑点状 病灶 脑标本 脑室周围白质 血管周围间隙 病理对照研究 梗塞灶 室管膜

本文对29例脑标本行 MRI-病理对照研究,其中18例脑标本 MRI 检查阳性,发现脑皮质下斑点状病灶(Subcortical Patchy Lesions,SPLs)95个。该病灶分两大类:第一类(64个)位于脑皮层下白质、基底核、小脑和脑干,其病理基础主要为血管周围间隙扩大(83%),小梗塞灶(11%),其他还有小动、静脉畸形(AVM),脱髓鞘灶和胶质增生灶;第二类(31个)位于侧脑室周围白质内,其病理基础为局部组织结构疏松呈空泡状,病灶相应部位的室管膜大片脱落。

In this paper, 29 cases of brain specimens MRI-pathology control study, of which 18 cases of brain specimens were positive MRI, found in the subcutaneous cortical lesions (Subcortical Patchy Lesions, SPLs) 95. The lesions were divided into two categories: the first one (64) located in the subcortical white matter, basal ganglia, cerebellum and brain stem, the main pathological basis for the expansion of the perivascular space (83%), small infarction (11%), There are other small animals, venous malformations (AVM), demyelination and glial hyperplasia; the second category (31) located in the periventricular white matter, the pathological basis for the local organization of loose loose vacuoles, lesions The corresponding part of the ependyma off.