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氧气从鼓室腔经圆窗膜扩散到内耳,称为中耳腔对内耳的充氧作用(oxygenation)。近年来的研究证明,外淋巴液氧张力与中耳氧张力成正比,耳蜗基底回多达10～15％的氧耗量来自中耳对内耳的充氧。在急性实验中,封闭圆窗,可致耳蜗缺氧,甚至引起150～7500Hz频率区的中度阈移。为探讨非耳毒性物质糊封圆窗对内耳功能的短期和长期影响,作者将12只SD大鼠分为4组,每组8只,经手术进入中耳腔,分别用矿物油、高粘度硅胶软膏、凡士
Oxygen diffuses from the tympanic cavity through the round window membrane into the inner ear, which is called the oxygenation of the inner ear. In recent years, studies have shown that the tension of the perilymph oxygen and the oxygen tension in the middle ear is proportional to the cochlear basal back up to 10 to 15% of the oxygen consumption from the middle ear oxygenation of the inner ear. In acute experiments, the round window can be closed, can lead to hypoxia of the cochlea, and even cause a moderate threshold shift in the frequency range of 150 ~ 7500Hz. In order to explore the short-term and long-term effects of non-ototoxic substances plaster round window on inner ear function, 12 SD rats were divided into 4 groups with 8 rats in each group. They were surgically inserted into the middle ear cavity with mineral oil, Silicone ointment, Vase