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呋喃西林(Nitrofurazone 或 Furacin)为一种呋喃属(Furan)的化学合成剂,具有强烈抑菌及杀菌作用。第二次世界大战时,临床上主要作为局部外用消毒剂,为外科、皮肤科、眼耳鼻咽喉科、泌尿科、口腔科、妇产科等所常用。近年来始应用于内科治疗细菌性痢疾、伤寒、百日咳,均有一定效果。本院于1959年治疗细菌性痢疾,大都采用合霉素,对发生抗药性的病例,或临床症状多日未见显著改善的患者,曾改用呋喃西林口服或再加用保留灌肠治疗。自6～9月,共收集以呋喃西林治疗细菌性痢疾131例,其中发生药疹者3例,兹作报导,以引起同志们的注意。
Nitrofurazone or Furacin is a Furan chemical synthesis agent with strong antibacterial and bactericidal activity. During the Second World War, clinically as a topical topical disinfectant for surgery, dermatology, eye and otolaryngology, urology, stomatology, obstetrics and gynecology and other commonly used. In recent years began to be used in medical treatment of bacterial dysentery, typhoid, pertussis, have a certain effect. The hospital in 1959 for the treatment of bacillary dysentery, most of the use of tetracycline, the occurrence of drug-resistant cases, or clinical symptoms have not seen significant improvement in patients over many days, had switched to nitrofurazone oral or re-use of retention enema treatment. From June to September, a total of 131 cases of bacillary dysentery treated with nitrofurazone were collected, of which 3 cases were drug eruptions. It is hereby reported that it attracted the attention of comrades.