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澳大利亚一所医院泌尿科报道，2例患者在短期内应用小剂量甲氨蝶吟和泼尼松或泼尼龙后引起膀联移行细胞癌（TCC）。1例为30岁女性，肿瘤为典型乳头状癌，在口服甲氨蝶吟每周5～15mg共10个月和泼尼松或泼尼松龙1年后出现症状。另1例患者55岁，发生多中心原位癌，口服甲氨蝶吟每?
Urology at a hospital in Australia reported that two patients developed bladder-line transitional cell carcinoma (TCC) after a short-term dose of methotrexate and prednisone or prednisolone. One case was a 30 year old female with a typical papillary carcinoma tumor that developed symptoms 10 to 15 mg weekly for methotrexate and 1 year after prednisone or prednisolone. Another case of patients 55 years old, occurred in multicentric carcinoma in situ, oral methotrexate every?