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干细胞被认为具有无限增殖和多向分化的潜能,骨髓干细胞不仅终生提供各种祖细胞和外周血细胞,而且还必须通过精细地调节自我更新和终末分化之间的动态平衡,避免因过度增殖导致白血病等癌症的发生或因过度分化造成储备干细胞的耗竭,使组织创伤的修复和自我更新上出现障碍。近年
Stem cells are thought to have the potential of immortal and multipotential differentiation. Bone marrow stem cells not only provide life-long progenitor cells and peripheral blood cells, but also must be able to prevent the hyper-proliferation caused by the fine adjustment of the homeostasis between self-renewal and terminal differentiation. The occurrence of cancers such as leukemia or the depletion of reserve stem cells due to over-differentiation has caused obstacles in the repair and self-renewal of tissue trauma. in recent years