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随着医学的发展、药物应用之广泛,药物所引起机体之损害亦日趋增多。药物可引起机体各脏器或各系统损害,由于有毒物质或药物进入机体引起肾脏机能和/或形态损害统称中毒性肾脏病。但亦有人将此名称之范围扩大,将由于生理代谢产物的浓度异常(如高尿酸血症、高血钾症、低血钾症等)所引起的肾脏损害,亦列入中毒性肾脏病中。本文仅就药物引起肾损害,而以“药源性肾脏病”一词讨论之。
With the development of medicine, a wide range of drug applications, the damage caused by the drug is also increasing. Drugs can cause damage to various organs or systems of the body. As a result of toxic substances or drugs entering the body causing renal dysfunction and / or morphological damage collectively referred to as toxic kidney disease. However, some people also extend the scope of this name to include renal damage caused by abnormal concentrations of physiological metabolites (such as hyperuricemia, hyperkalemia, hypokalemia, etc.) and are also included in toxic kidney disease . This article deals only with drug-induced kidney damage, but with the term “drug-induced kidney disease.”