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目的:研究注射用门冬氨酸洛美沙星药物不良反应/事件(ADR)病例,为临床合理用药提供参考。方法:从病患基本情况、注射门冬氨酸洛美沙星前后的临床表现、出现的不良反应等方面对265例注射用门冬氨酸洛美沙星ADR报告进行原患疾病及用药之间的因果关系的回顾性统计分析。结果:注射用门冬氨酸洛美沙星药物会损害人体某些系统,主要体现在皮肤及其附件、消化系统、中枢神经呼吸系统等。药物在5～40min内发生不良反应,产生效果时间为停药后1d内。结论:临床上使用注射用门冬氨酸洛美沙星药物会使患者产生不良反应,医院应重视对病患的监护,减少或者避免ADR病例的发生。
Objective: To study the cases of aspirin aspartate adverse drug reaction (ADR) and provide a reference for clinical rational drug use. Methods: Based on the basic information of patients, the clinical manifestations before and after the injections of Lomefloxacin aspartate, the adverse reaction, 265 patients with ADR reported by Lomefloxacin aspartate Retrospective Statistical Analysis of Causality. Results: Injection of Lomefloxacin aspartic acid could damage certain systems in the human body, mainly in the skin and its appendages, digestive system and central nervous system respiratory system. Drug adverse reactions occurred within 5 ~ 40min, the effect of time within 1d after stopping. Conclusion: The clinical use of aspartic acid injection of Lomefloxacin drugs will cause adverse reactions in patients, the hospital should pay attention to the patient’s care, reduce or avoid the occurrence of ADR cases.