Rapid detection of the known SNPs of CYP2C9 using oligonudeotide microarray

• 作 者: Si-YuanWen HuiWang Ou-JunSun S
• 机 构: BeijingInstituteofRadiationMedicine
• 出 处: 世界胃肠病学杂志：英文版（电子版）
• 发表日期: 2003年6期
• 关键词: CYP2C9 单核苷多态性 寡核苷酸微阵列分析 等位基因

AIM: Cytochrome P450 2C9 (CYP2C9) is a polymorphic enzyme responsible for the metabolism of a large number of dinically important drugs. Individuals with mutant enzymes may risk serious side effects under routine therapy with certain drugs metabolized by