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目的 :观察绝经后应用小剂量利维爱妇女血浆蛋白、血糖和血脂的变化。方法 :检测 6 0例妇女用药 3,6 ,12和 2 4个月时的血浆白蛋白 (A)、球蛋白 (G)、血糖 (GL)、总胆固醇 (TC)、甘油三脂 (TG)、高密度脂蛋白(HDL)和低密度脂蛋白 (LDL)。结果 :用药 6个月时A升高 ,以 12个月时升高最明显 (P <0 .0 1)。用药 3个月后TG显著降低 (P <0 .0 5～ 0 .0 1)。HDL用药 3个月时有所降低 (P >0 .1) ,以后渐恢复至用药前水平。用药后G、GL、TC、LDL无明显变化 ,但GL、TC降低的妇女多于升高者。结论 :小剂量利维爱可使绝经后妇女A升高 ,明显降低TG ,对G、GL、TC、HDL、LDL无明显影响。
Objective: To observe the changes of plasma protein, blood glucose and blood lipids in postmenopausal women with low-dose Levi. Methods: The levels of plasma albumin (A), globulin (G), blood glucose (GL), total cholesterol (TC) and triglyceride (TG) were measured at 6, 12 and 24 months after treatment in 60 women. , High density lipoprotein (HDL) and low density lipoprotein (LDL). Results: A increased at 6 months and increased most significantly at 12 months (P <0.01). After 3 months of treatment, TG was significantly lower (P <0.05 ~ 0.01). HDL medication decreased at 3 months (P> 0. 1), then gradually returned to the level before treatment. After treatment, G, GL, TC, LDL no significant change, but GL, TC decreased more women than those who rose. CONCLUSION: Levofloxacin can elevate A, decrease TG and have no significant effect on G, GL, TC, HDL and LDL in postmenopausal women.