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为研究急性心肌缺血时大鼠延髓内脏带（ＭＶＺ）内ＳＰ受体的分布及形态学变化，采用ＡＢＣ法对静脉注射垂体后叶素后的大鼠延髓进行了抗ＳＰ受体（ＳＰＲ）或抗Ｆｏｓ蛋白免疫组织化学染色，或Ｆｏｓ／ＳＰＲ双重免疫组织化学染色。发现静脉内注射垂体后叶素诱发急性心肌缺血后，在双侧ＭＶＺ内出现Ｆｏｓ阳性神经元；在锥体交叉（ＰＹＸ）和最后区（ＡＰ）水平，ＳＰＲ免疫反应结构（ＳＰＲ－ＬＩ）较未注射组明显增强，背内侧部迷走神经运动背核（ｎｍｄＸ）的ＳＰＲ－ＬＩ纤维也由弯曲的粗纤维（羊毛型）变为细的直纤维。３０％左右的ＳＰＲ－ＬＩ阳性神经元可能参与静脉注射垂体后叶素后引起的心血管应激反应的传导或调控。
In order to study the distribution and morphological changes of SP receptors in the medullary visceral zone (MVZ) of rats with acute myocardial ischemia, the anti-SP receptor (SPR) activity was measured in the medulla oblongata of rats by intravenous injection of vasopressin Or anti-Fos protein immunohistochemical staining, or Fos / SPR dual immunohistochemical staining. Found that Fos-positive neurons were found in bilateral MVZs after intravenous injection of pituitrin-induced acute myocardial ischemia. SPR immunoreactive structure (SPR-LI) was detected at the level of pyramidal cross (PYX) Compared with the non-injected group, the SPR-LI fibers in the medial dorsal vagal motor nucleus (nmdX) also changed from curly coarse fibers (wool type) to fine straight fibers. About 30% of SPR-LI-positive neurons may be involved in the conduction or regulation of cardiovascular stress caused by intravenous injection of vasopressin.