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本文应用多种技术相配合的方法,观察了曼氏血吸虫病鼠在治疗前后门脉系统的变化。取重20～22g的瑞士远交小鼠83只,每鼠接种尾蚴约30条。感染后第50天,粪检全部阳性。感染后60天随机取10鼠剖杀,由门脉肠系膜血管中检获7～11条成虫(雌雄数几乎相等)。于感染后70天剖杀另一组鼠作为感染对照,其余均先用100mg/kg一次剂量的羟氨喹治疗。一周后再用80mg/kg的海蒽酮一次肌注治疗。将治疗鼠分为:1.治毕后1月组,2.治毕后2月组,3.治毕后6月组。包括正常对照的所有动物,在剖杀后均作以下技术指标的观察:1.门脉血管模型;在乙醚麻醉下处死小鼠,用注射器将经钙蓝油(calco blue oil)着色的12%乙烯醋酸丙酮溶液直接注入门脉主干内,适当加压,使肝内
In this paper, we used a variety of techniques to observe the change of portal vein system in Schistosoma mansoni before and after treatment. Twenty-three Swiss swingers, weighing 20-22 g, were inoculated with about 30 cercariae per mouse. 50 days after infection, fecal examination was all positive. Sixty days after infection, 10 rats were killed randomly and seized from 7 to 11 adults in portal mesenteric vessels (almost equal in number of males and females). Another group of mice was killed 70 days after infection as an infection control, and the rest were treated with a single dose of 100 mg / kg of hydroxyquramine. One week later with 80mg / kg of sea anthrone intramuscular treatment. Treatment of mice will be divided into: 1. After treatment in January group, 2. After treatment group in February, 3. After treatment group in June. All animals, including the normal controls, were observed for the following technical indicators after dissection: 1. Portal vein models; mice were sacrificed under ether anesthesia and the calco blue oil-colored 12% Ethylene acetic acid acetone solution directly into the main portal vein, appropriate pressure to the liver