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在历史的车轮滚入本世纪的前夕,生物学家研究细胞的聚焦点已开始从细胞质转向细胞核。人们把细胞核视为主管遗传的中心,认识到染色质是与遗传有的物质。“染色质”(Chromatin)这个词由 W.Fle-mming 在1879年首次提出,用它来指细胞核里一种易被染料着色的微粒状物质,当时生物学家为解决染色质化学性质的问题而绞尽脑汁。事实上,这个问题早在十年前就有人作了回答,这人就是瑞士杰出的生理学家和生物化学家 F.Miescher。Miescher 1844年8月13日生于瑞士的巴赛尔,他的父亲是位开业医生,并担任过伯尔尼大学病理解剖学教授,米歇尔早年就随父学医。然而,对米歇尔科学生涯影响最大的是他的叔叔 W.His。这位当时著名的解剖学家和组织学家认为,“组织发育的根本问题只有依靠化学的方法才能解决”。他极力鼓励年
On the eve of the passage of the wheel of history into the century, the focus of biologists’ research cells has begun to shift from the cytoplasm to the nucleus. People regard the nucleus as the center of inheritance, recognizing that chromatin is something that is inherited. The word “Chromatin” was first proposed by W. Fleming in 1879 to refer to a particulate substance in the cell nucleus that is easily dye-colored, when biologists addressed the problem of chromatin chemistry And brains. In fact, the question was answered as early as ten years ago by F. Miescher, Switzerland’s distinguished physiologist and biochemist. Miescher was born in Basel, Switzerland on August 13, 1844. His father, a practicing doctor and a professor of pathological anatomy at the University of Bern, had studied medicine with his father in his early years. However, his greatest influence on Michelle’s scientific career is his uncle W.His. The famous anatomist and organizational scientist at the time believed that “the fundamental problem of tissue development can only be solved by chemical means.” He strongly encouraged the year