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目的通过对本院收治的重症手足口病患儿的临床症状进行分析,了解早期临床特点,总结救治经验,为临床上该疾病的诊断和治疗提供依据。方法回顾性分析本院儿科2009年5月至2010年9月收治的78例重症手足口病患儿的临床资料,主要内容为病情、实验室指标、救治方案。结果 78例患儿均为EV71感染,6例为3期A期病例,其余均为2期病例,早期的临床症状有持续高热、呕吐、皮疹、头痛及精神萎靡,其中有抽搐1例,脑疝4例,均伴有神经系统症状,给予相应的救治后,均治愈。结论重症手足口病救治的关键时期为2期和3期A,临床症状主要有发热、头痛等精神症状,给予降颅压,静脉大剂量丙种球蛋白和酌情使用激素可有效的治疗重症手足口病。
Objective To analyze the clinical symptoms of children with severe hand-foot-mouth disease admitted to our hospital, understand the characteristics of early-stage clinical and summarize the experience of treatment and treatment, and provide the basis for the diagnosis and treatment of this disease in clinic. Methods The clinical data of 78 children with severe hand-foot-mouth disease admitted to our hospital from May 2009 to September 2010 were retrospectively analyzed. The main contents were the condition, laboratory indexes and treatment plans. Results 78 cases of children were EV71 infection, 6 cases were 3 stage A cases, the rest were 2 cases, the early clinical symptoms of persistent fever, vomiting, rash, headache and apathetic, including convulsions in 1 case, brain Hernia in 4 cases, are associated with neurological symptoms, given the appropriate treatment, were cured. Conclusions The critical period for the treatment of severe hand-foot-mouth disease is stage 2 and stage 3. The clinical symptoms include fever, headache and other psychiatric symptoms. Intracranial pressure, intravenous high-dose gamma-globulin and hormone may be used to treat severe hand, foot and mouth disease.