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观察Ｇｒａｖｅｓ病患者（ＧＤ）空腹血浆ＰＴＨ、ＣＴ、钙与正常组无明显差异，而１α，２５（ＯＨ）_２Ｄ较对照组低，ＧＤ患者一次静脉注射葡萄糖酸钙及ＥＤＴＡ后血浆ＰＴＨ、ＣＴ、１α，２５（ＯＨ）_２Ｄ、钙、磷浓度的动态变化。ＧＤ患者于ＣａＧ及ＥＤＴＡ试验中血钙波动较为显著，而ＰＴＨ、１α、２５（ＯＨ）_２Ｄ无明显动态变化，甲状腺Ｃ细胞第二相分泌较差。提示ＧＤ应变情况下血钙的波动更多的受ＰＴＨ、ＣＴ以外甲状腺激素等因素的影响，或甲状腺激素可能提高ＰＴＨ活性。亦提示患者有维生素Ｄ代谢异常。
The levels of PTH, CT and calcium in fasting plasma of patients with Graves disease (GD) were not significantly different from those in the normal group, while the values of 1α, 25 (OH) _2D were lower in the GD patients than those in the control group. After a single intravenous injection of calcium gluconate and EDTA, 1α, 25 (OH) _2D, calcium, phosphorus dynamic changes. In GD patients, the fluctuation of serum calcium in CaG and EDTA was significant, while there was no obvious dynamic change in PTH, 1α, 25 (OH) _2D and the second phase secretion in thyroid C cells was poor. Prompt GD strain of calcium fluctuations more affected by PTH, CT other than thyroid hormone, or thyroid hormone may increase PTH activity. Also prompts patients with abnormal vitamin D metabolism.