吸入性损伤犬高频喷射通气时呼吸气流与CO_2排出关系的初步探讨

来源 :江西医学院学报 | 被引量 : 0次 | 上传用户:maotian1
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为观察吸入性损伤犬高原喷射通气时时吸气流与CO_2排出关系,本文选健康大6只,静脉麻醉后,插气管导管,用三维粒子动态分析仪测定自主呼吸时吸气和呼气流速,并采集动脉血标本进行血气分析。静注司可林,当动物呼吸停止时,通入高压蒸气5s,然后随机进行五种不同条件高频喷射通气。每种通气模式通气20min,观察呼气速度Ve、吸气速度Vi的变化。根据公式Re=Vrp/η计算出雷诺数,同时观察PaCO_2、PaO_2、PIP的变化。结果:(1)自主呼吸时吸气为层流,呼气可能为层流,也可能为涡流;(2)高频喷射通气(HFJV)时呼气和吸气气流均为涡流;(3)高频双向喷射通气(HFTJV)与HFJV相比,呼气流速显著增加(P<0.05),PaCO_2显著降低(P<0.05),呼气流速与PaCO_2呈质相关(r=-0.9216,P<0.05),同时吸气流速也有增加的趋势。提示:HFJV可维持吸入性损伤犬的正常通气,其机制可能与涡流有关。HFTJV是在HFJV基础上增加了反向喷射气流,可以增进呼吸气流速度,促进CO_2排除。 In order to observe the relation between the inspiratory flow and the CO 2 excretion of inhalation injury dog ​​plateau jet ventilation in this paper, six healthy individuals were selected. After intravenous anesthesia, the endotracheal tube was intubated, and the inspiratory and expiratory flow rates during spontaneous respiration were measured by three- Blood samples were collected for blood gas analysis. Intravenous Secretary Ke Lin, when animal breathing stopped, access to high-pressure steam 5s, and then randomly selected five different conditions of high-frequency jet ventilation. Ventilation of each ventilation mode 20min, observe the expiratory velocity Ve, inhalation velocity Vi changes. The Reynolds number was calculated according to the formula Re = Vrp / η, and the changes of PaCO_2, PaO_2 and PIP were also observed. Results: (1) Aspiration was laminar flow during spontaneous breathing, and the expiration could be laminar or vortex; (2) When the HFJV was exhaled and the inspiratory air flow was vortex; (3) Compared with HFJV, high-frequency two-way jet ventilation (HFTJV) significantly increased the expiratory flow rate (P <0.05) and PaCO 2 (P <0.05) .9216, P <0.05), while the inspiratory flow rate also increased. Hint: HFJV can maintain the normal ventilation of dogs with inhalation injury, the mechanism may be related to eddy currents. HFTJV is based on the HFJV added reverse jet airflow, can enhance the respiratory airflow speed, promote CO 2 exclusion.
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