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目的探讨纤维支气管镜下局部灌注治疗支气管内膜结核(EBTB)的临床疗效。方法将我院收治的经纤维支气管镜确诊的60例支气管内膜结核患者随机分为对照组30例和治疗组30例,对照组常规使用全身抗结核治疗加超声雾化治疗,治疗组在对照组基础上加用纤维支气管镜下局部治疗,比较2个月后两组治疗方法的疗效。结果治疗组和对照组肺部病变吸收率分别为79.2%,40.9%(χ2=7.05,P(0.01);纤支镜有效率分别为86.2%,41.9%(χ2=12.6,P(0.01);痰菌阴转率分别92.9%,55.6%(χ2=10.08,P(0.01)。两组比较均有显著性差异。结论在全身抗结核治疗基础上加纤维支气管镜下局部灌注抗痨药物治疗支气管内膜结核的临床疗效较单纯全身抗痨治疗好。
Objective To investigate the clinical effects of local bronchofibroscopy in the treatment of endobronchial tuberculosis (EBTB). Methods Sixty cases of endobronchial tuberculosis diagnosed by bronchofiberscopy in our hospital were randomly divided into control group (n = 30) and treatment group (n = 30). Patients in the control group were treated with general antituberculous therapy plus ultrasonic atomization, while those in the control group Group based on the use of local bronchoscopy, compared two months after the treatment of two groups. Results The lung lesions absorption rates in the treatment group and the control group were 79.2% and 40.9%, respectively (χ2 = 7.05, P <0.01). The effective rates of bronchoscopy were 86.2% and 41.9% (χ2 = 12.6, P <0.01); The sputum negative conversion rate was 92.9% and 55.6% respectively (χ2 = 10.08, P (0.01)) .Conclusion The systemic anti-TB therapy based on local bronchoscopic anti-tuberculosis drug therapy bronchial tube The clinical efficacy of endometrial tuberculosis than systemic anti-tuberculosis treatment is good.