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采用放射受体分析方法测定了42例脑梗死病人急性期与恢复期血清及脑脊液(CSF)ν-氨基丁酸(GABA)水平,发现脑梗死急性期CSF内GABA含量显著高于恢复期及对照组(P<0.001);CSF内GABA含量与脑梗死面积大小有关,梗死面积愈大,CSF内GABA水平愈高。血清GABA含量梗死组在急性期和恢复期与对照组比较均无明显差异,血清和CSF内GABA含量之间无任何相关性。
Radioimmunoassay was used to determine the levels of serum and cerebrospinal fluid (CSF) ñ-GABA in 42 patients with acute cerebral infarction. The levels of GABA in CSF during acute cerebral infarction were significantly higher than those in recovery and control (P <0.001). The content of GABA in CSF was related to the size of cerebral infarction. The larger the infarct size, the higher the level of GABA in CSF. Serum GABA levels in infarction group in the acute phase and recovery phase compared with the control group were no significant difference between serum and CSF GABA content without any correlation between.